Predilin Tablet 5mg is a prescription corticosteroid medication containing Prednisolone as its active pharmaceutical ingredient. It provides potent anti-inflammatory and immunosuppressive effects for treating various inflammatory and autoimmune conditions.
Uses
Predilin Tablet 5mg is prescribed for treating inflammatory and autoimmune conditions including asthma, rheumatoid arthritis, inflammatory bowel disease, skin disorders, allergic reactions, multiple sclerosis flares, lupus, nephrotic syndrome, and certain types of cancer. It also helps prevent organ transplant rejection.
Benefits
- Powerful anti-inflammatory properties
- Effective immunosuppressive action
- Rapid relief of inflammatory symptoms
- Reduces tissue swelling and inflammation
- Alleviates pain in inflammatory conditions
- Controls autoimmune disease flares
- Manages severe allergic reactions
- Improves quality of life during inflammatory episodes
- Well-established clinical efficacy
How It Works
Predilin Tablet 5mg works by entering cells and binding to glucocorticoid receptors, which alters gene expression. This results in decreased production of inflammatory mediators, reduced immune cell activity, and inhibition of inflammatory processes throughout the body, leading to symptom relief.
Duration of Action
Effects begin within 1-2 hours after administration, with anti-inflammatory benefits lasting approximately 24-36 hours per dose. The biological half-life ranges from 12-36 hours, allowing for once-daily dosing in many treatment protocols.
Dosage
Condition | Recommended Dosage | Frequency |
---|---|---|
Acute conditions | 20-60mg | Once daily |
Chronic conditions | 5-15mg | Daily/alternate days |
Children | 0.5-2mg/kg | Daily or divided |
Maintenance | 2.5-10mg | Daily/alternate days |
Warnings
Never discontinue Predilin Tablet 5mg abruptly after prolonged use. Long-term use may lead to serious side effects including osteoporosis, diabetes, increased infection susceptibility, and adrenal suppression. Contraindicated in patients with untreated infections, systemic fungal infections, or hypersensitivity to components.
Side Effects
Common effects include increased appetite, fluid retention, mood changes, insomnia, weight gain, high blood pressure, elevated blood glucose, muscle weakness, skin thinning, easy bruising, and increased vulnerability to infections. Psychological effects may include mood swings and depression.
Pregnancy and Breastfeeding
Predilin Tablet 5mg should be used during pregnancy only if potential benefits justify potential risks to the fetus. Prednisolone passes into breast milk and may affect nursing infants. Consult healthcare providers before using while pregnant or breastfeeding.
Interactions
- NSAIDs (increased gastrointestinal bleeding risk)
- Anticoagulants (altered effectiveness)
- Antidiabetic medications (reduced efficacy)
- CYP3A4 inhibitors/inducers (altered drug levels)
- Live vaccines (compromised immune response)
- Diuretics (electrolyte imbalances)
- Digoxin (increased toxicity risk)
- Certain antibiotics (altered effectiveness)
Precautions
Take Predilin exactly as prescribed. Take with food to minimize stomach irritation. Carry medical identification indicating corticosteroid use. Avoid exposure to infections. Regular monitoring of blood pressure, blood glucose, and bone density recommended during long-term therapy.
Important Information
Use Predilin Tablet 5mg at the lowest effective dose for the shortest duration possible. Follow tapering schedules when discontinuing. This medication may mask infection signs, so report any new symptoms promptly to your healthcare provider.
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